HFSP-funded Postdoc Position in EPR Spectroscopy

The Molecular Biomechanics group at the Heidelberg Institute for Theoretical Science and the IMSEAM, Heidelberg University, seeks a postdoctoral fellow to investigate protein mechanoradicals.

The overarching aim of the HFSP project is to test our hypothesis that mechanically- generated radicals form within the extracellular matrix of living systems and affect their physiology. You will closely collaborate with the labs of Ronen Zaidel-Bar, Tel Aviv University, and Alex Dunn, Stanford University, where our hypothesis will be tested in two different in- vivo model. The ultmate goal is to establish mechanoradicals as a hitherto unrecognized molecular species in life that converts tension into chemical signals, with implications for tissue homeostasis, organism health and ageing.

The aim of your project is to uncover the biophysical principles of mechanoradical forma8on and downstream signalling. To this end, you will employ Electron paramagnetic resonance (EPR) spectroscopy methods, tissue rheology, redox biochemistry techniques. If interested, you can combine these with machine learning and molecular simulation methods we develop in our group. Your work will be tightly linked to our ongoing efforts within our ERC project RADICOL.

Your profile

• PhD degree in biochemistry, biophysics, or related fields

• Solid skills in EPR spectroscopy
• Strong interest in protein radicals and their fate
• Enthusiasm for international teamwork

We are a highly interdisciplinary and diverse group of scientists and provide an excellent and collaborative research environment. Please reach out for any further questions. Send your CV, your publication list, a short research statement, and contact info for three referees to Frauke Graeter: [email protected]

Sami Jannin is looking to hire 2 Post-Docs to develop innovative hyperpolarization methods at the CRMN in Lyon, France.
If you have previous experience in DNP or pulsed EPR,  then these might be good opportunities for you.  If you’re interested, send your CV to sami.jannin@univ-lyon1.fr
Project 1 : Pulsed DNP with hyperpolarizing matrices (HYPSO and HYPOP)
📌 The work is to develop experimental methods to boost the NMR sensitivity using the combination of pulsed DNP and innovative hyperpolarizing materials
  • Work on a brand new Bruker Pulsed EPR system equipped with NMR detection.
  • Develop groundbreaking hyperpolarization methods for rapid 1H & 13C DNP using novel hyperpolarization matrices.
  • Ultimately combine pulsed-DNP with our rapid freeze/melt/flow benchtop DNP setup currently under development.
  • Co-supervise PhD students.
Project 2 : Hyperpolarization transport
📌 The work is to combine hyperpolarizing matrices and state-of-the-art low-temperature DNP methods, both available in our laboratory, to extend hyperpolarization lifetimes and ultimately transport hyperpolarized samples to a pre-clinical MRI facility.
  • Participate in the MRI experiments (metabolic imaging in rodents).
  • Co-supervise PhD students.
– – –
🏢 World-class facilities at the CRMN-Lyon in the HMRLab team
📑 Check recent publications
‘Benchtop DNP polarizer’ ChemRxiv (2024) 
‘Easy hyperpolarization transfer’ J. Am. Chem. Soc. 145, 27576–27586 (2023) 
’Spin diffusion near the election’ Sci. Adv. 7, eabf5735 (2021) 
‘Innovative hyperpolarizing matrix’ Nat. Commun. 12, 1–9 (2021) 
‘3D printed DNP-NMR probe’ J. Magn, Reson Open 10–11, 1–12 (2022) 
‘Fast hyperpolarized solution transfer system’ J. Magn. Reson. Open 8–9, 1–10 (2021) 
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PhD position Unraveling a new copper resistance mechanism in bacteria

Copper (Cu) is required in different key metabolisms like respiration and photosynthesis, yet Cu is cytotoxic even at low concentrations. Human activities lead to Cu accumulation in the environment that is a threat to health and ecosystems, and it contributes to the emergence of Cu resistant organisms. Understanding bacterial Cu homeostasis diversity is therefore highly relevant since it could provide valuable targets for novel antimicrobial treatments. This project aims at describing an original Cu resistance mechanism of environmental and pathogenic bacteria. This mechanism occurs under anaerobiosis or micro-aerobiosis and involves the periplasmic cuproprotein CopI and potential partners yet to be identified. CopI is highly induced by Cu and possess a scarce green type cupredoxin site. In this project, we will study the CopI proteins from three models: the environmental bacterium Rubrivivax gelatinosus and the pathogenic bacteria Vibrio cholerae and Pseudomonas aeruginosa. These homolog proteins exhibit differences in their three Cu-binding modules (the cupredoxin site and two other His and His/Met rich regions). To reach our objective, we will produce and purify the WT proteins as well as several mutants. The different Cu sites will be fully characterized, in particular by state-of-the-art magnetic resonance spectroscopy (EPR and NMR). Redox properties and electron transfer pathways will be studied. Two potential partner proteins, selected from genome analysis, will also be studied. These proteins will be characterized in details and protein-protein interaction with CopI will be evaluated by different means. Altogether, this project will improve knowledge on Cu proteins, Cu metabolism and how bacteria resist a Cu stress.

The PhD project will exploit metal coordination chemistry, biochemistry and spectroscopy. The student will be involved in protein production and purification, biochemistry studies, redox titrations, UV-visible and advanced EPR spectroscopy.
Expected profile of the candidate
The candidate must have a Master 2 in chemistry or physical chemistry and a strong interest of the chemistry/biology interface, with good practical skills in bioinorganic chemistry and spectroscopic techniques. We are looking for a rigorous and versatile candidate, with a capacity for teamwork and skills for written and oral communications in French and/or English.

Send CV and motivation letter to Pierre Dorlet ([email protected])
Team webpage: https://bip.cnrs.fr/groups/bip07 PI webpage: https://bip.cnrs.fr/contact/pierre-dorlet
École Doctorale des Sciences Chimiques, Aix-Marseille Université https://ecole-doctorale-250.univ-amu.fr/
Expected starting date : Fall 2024

Postdoctoral Position in Molecular Spin-Optical Dynamics
Background to the position.
The Quantum Optospintronics Group explores the spin and optical properties of molecular materials and devices with applications spanning energy harvesting, quantum information processing, and sensing. The lab houses state-of-the art spin-optical measurement capabilities and as part of a dynamic group, you will have significant opportunities to shape, and take responsibility for an exciting research agenda.About the role.
Through this position, you will pioneer ways to unlock the versatility of molecular spin systems for photonic devices and quantum sensing. Your work will help to unravel the spin-dependent phenomena underpinning next-generation molecular optoelectronic/photonic materials and contribute to the development of novel spin-enhanced molecular sensors. You will deploy advanced spin-optical techniques, play a leading role in international collaborations, and have significant autonomy and opportunities for learning.

We particularly welcome applications from candidates from under-represented groups, and are committed to fostering an inclusive, supportive, and flexible working environment in all our activities.

For further details see: https://www.jobs.ac.uk/job/CZV701
Closing date: 13th June 2023
Location: The University of Glasgow, Scotland, UK
Funding is available for up to three years
Contact Dr. Sam Bayliss ([email protected]) for informal enquiries.

Professor (W3) of Physical Chemistry (Magnetic Resonance with focus on Electron Paramagnetic Resonance (EPR) spectroscopy)

Goethe University Frankfurt am Main invites applications for the above position at the Institute of Physical and Theoretical Chemistry within the Faculty of Biochemistry, Chemistry and Pharmacy. This civil servant or public employee position will be filled at the earliest opportunity.

We seek to appoint an internationally outstanding researcher in the field of magnetic resonance with focus on EPR spectroscopy and/or diverse hyperpolarization techniques, who is expected to represent and develop these methods within a broad scope. The candidate should have a proven track record in method development (theory and experiment) and a well-defined profile in a relevant application area in chemistry, biochemistry or physics, with preference for the (bio)molecular sciences. Various joint initiatives are open for participation within the profile areas of Goethe University, i.e., “Structure and Dynamics of Life” and “Time, Space, Matter”. Notably, the candidate is encouraged to establish collaborations within the SFB 1507 “Membrane-Associated Protein Assemblies, Machineries, and Supercomplexes”, the Cluster of Excellence project “SCALE – Subcellular Architectures of Life”, or other ongoing initiatives. The professorship is associated with the renowned Center for Biomolecular Magnetic Resonance Spectroscopy (BMRZ) of Goethe University and is meant to represent its third methodological pillar, besides solution-phase and solid-state NMR spectroscopy. Possible cross-linkages result from joint application projects, e.g., in the fields of hyperfine spectroscopy or hyperpolarization, which are to be further developed.

The position holder will be involved in teaching (lectures, seminars and practical courses) in the Bachelor and Master program in Chemistry and should represent the subject Physical Chemistry within its full scope.

The formal hiring requirements are defined in sections 67 and 68 of the Hessian Higher Education Act (Hessisches Hochschulgesetz).

Goethe University is an equal opportunity employer, committed to diversity and inclusion. In particular, we are welcoming applications by qualified women and people with a migrant background. At Goethe University, a special emphasis is placed on creating and sustaining a family-friendly work and research environment. Where applicants are otherwise equally qualified, preference is given to candidates with disabilities or equivalent. The same applies to women in fields in which they are under-represented.

To apply, please send a CV, a list of publications, an overview of your research and teaching activities as well as transcripts and a selection of recent course evaluations as a single PDF document by 18 May 2023 to [email protected]. Further information about the appointment process, the legal framework and data protection: www.professorship-vacancies.uni-frankfurt.de.

EPR Application Scientist – Bruker BioSpin EPR Team in Ettlingen, Germany


New opportunity based in Ettlingen, Germany for an Application Scientist to join the Bruker BioSpin EPR Applications Team and perform a wide range of responsibilities involving the EPR spectrometers, including instrument demonstrations, sales support, in house and on site customer training, in house and onsite customer support, and development of new methods.

For more information and application form please visit the online portal at: https://englishcareers-bruker.icims.com/jobs/13380/application-scientist/job?mobile=false&width=1902&height=500&bga=true&needsRedirect=false&jan1offset=60&jun1offset=120

Assistant Project Scientist in Biological Magnetic Resonance

Assistant Project Scientist position available in Dr. Songi Han’s lab. A doctorate degree in Chemistry, Physics, Biology, or related field, along with a minimum of 2 years work experience performing research or managing projects in academia or industry and a strong publication record required. UCSB is an AA/EOE, including disability/vets. For details, https://recruit.ap.ucsb.edu/JPF02371

EPR Application Scientist – Bruker BioSpin EPR Team

New opportunity based in Billerica, MA for an Application Scientist to join the Bruker BioSpin EPR Applications Team and perform a wide range of responsibilities involving the EPR spectrometers, including instrument demonstrations, sales support, in house and on site customer training, in house and onsite customer support, and development of new methods. For more information, please visit: https://social.icims.com/viewjob/pt1666170981411f2e8c

Post-Doctoral position in Liquid State DNP NMR
A postdoctoral fellowship position is available at the U.S. National High Magnetic Field Laboratory (National MagLab) / Florida State University in Tallahassee, Florida. This position provides a unique opportunity to conduct Dynamic Nuclear Polarization experiments in the liquid state, with the aim of increasing the sensitivity of liquid-state NMR on large volume samples and at high magnetic fields. The postdoctoral candidate will be supported by funding recently received from the National Science Foundation, with yearly contracts renewable by mutual agreement for up to 3 years. The candidate will work with a multidisciplinary team of scientists and engineers affiliated to the MagLab NMR and EPR programs, and via collaborations with renowned experts in the field of magnetic resonance. The research will focus primarily on conducting DNP experiments employing a Gyrotron-equipped NMR spectrometer at 14. 1T in the NMR division, as well as on experiments on other variable (high) field EPR machines using lab-built instrumentation.

An optimal candidate for this position will have received or is about to receive a Ph.D. and possesses knowledge in experimental and/or theoretical fields pertaining NMR, DNP, or EPR spectroscopy. To apply, please send a CV, a list of publications and three letters of reference to Dr. Sungsool Wi ([email protected]) or Dr. Thierry Dubroca ([email protected]). Review of applications will begin September 1, 2022 and continue until the position is filled. Applicants can also apply to Florida State University at https://jobs.fsu.edu, Job # 52804. If you are a current FSU employee, apply via myFSU > Self Service. Additional screening will apply to foreign nationals.

For additional information, contact:

Bettina Roberson:
[email protected]
National High Magnetic Field Laboratory, Florida State University,
1800 E. Paul Dirac Drive
Tallahassee, FL 32310-2740
National High Magnetic Field Laboratory (NHMFL) is operated for the National Science Foundation by a collaboration of institutions comprising Florida State University, the University of Florida, and Los Alamos National Laboratory.

The NHMFL is operated for the National Science Foundation by a collaboration of institutions comprising FSU, UF, and LANL. FSU is an Equal Opportunity/Access/Affirmative Action/Pro Disabled & Veteran Employer. We encourage women and all underrepresented racial and ethnic groups to apply. FSU’s Equal Opportunity Statement can be viewed at: http://www.hr.fsu.edu/PDF/Publications/diversity/EEO_Statement.pdf

Bridge12 is hiring

Bridge12 is hiring. We are currently looking for a junior scientist to work on multidisciplinary projects covering large aspects of magnetic resonance, instrumentation design, development of prototypes and conduct research. The position requires creativity in a wide range of areas of magnetic resonance spectroscopy including NMR and EPR spectroscopy, imaging, and instrument development.

We are looking for a highly motivated, highly organized individual who enjoys an innovative, interdisciplinary environment and the challenges that come with manufacturing high-tech, scientific instrumentation. You will work out of the Bridge12 facilities in Natick MA with only occasional travel for conferences.

For more information, please visit:

PhD student or Postdoc @ MPI CEC

The EPR research group at MPI CEC is looking for a
PhD student or Postdoc (m/f/div) in EPR spectroscopy
The position is available from September 1st 2022. The doctoral researcher will work on a 3-year-doctoral-program and the postdoctoral position is initially for 24 months, with the possibility of an additional one-year renewal.
Your tasks:
The appointed researcher will utilize and further develop advanced (in situ) EPR techniques to understand active sites in solid state and molecular catalysts, and the generation of radical intermediates during catalytic action. The EPR group at MPI CEC employs electron paramagnetic resonance (EPR) techniques to monitor and characterize paramagnetic states relevant in energy conversion and storage processes. We develop and apply state-of the art EPR spectrometers ranging from GHz to THz frequencies. This position thus provides the possibility to conduct pioneering research at the interface of spectroscopy and catalysis research.
Your qualifications:
For the PhD position, we require the Master’s degree certificate and for the postdoctoral position, we also require the PhD degree in physics/physical chemistry or a related discipline. The candidate should have a strong background in spectroscopy (ideally magnetic resonance), inorganic chemistry, and a sound foundation in basic concepts of quantum mechanics and the design of scientific instruments.
Our offer:
We offer an international, dynamic working environment in a renowned research institute, family-friendly jobs and flexible working hours. The PhD will be remunerated according to the Max Planck Society´s funding guidelines for junior scientists and the postdoctoral position according to TVöD (Bund) in line with your qualifications and professional experience.
The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Furthermore, the Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.
Your detailed application should include a cover letter with description of past experience, a curriculum vitae with the contact details of three referees and a copy of your degree certificate. If we have aroused your interest then please send your application preferably in digital form until 22nd of August 2022 stating the reference code AS014 to:
Dr. Alexander Schnegg Max Planck Institute for Chemical Energy Conversion Stiftstrasse 34-36 45470 Muelheim an der Ruhr Germany

Post Doc @ Hoffman Lab

Post Doc @ Hoffman Lab


Post-doctoral positions in the group of

Professor Brian M. Hoffman of Northwestern University.

We determine the catalytic mechanisms of metalloenzymes through the development and implementation of electron-nuclear double resonance (ENDOR) spectroscopy, a combination of NMR and EPR. This technique is uniquely able to determine active site composition and electronic and geometric structures, not merely for an enzyme resting state but, most importantly, for key trapped catalytic and photogenerated intermediates. Characterization of key intermediates reveals mechanism!

Among the array of projects reflected in recent publications are ongoing studies of multiple central issues at the intersections of Inorganic Chemistry/Biochemistry/Biology. (i) Biological ‘nitrogen fixation’ – the reduction of N2 to two NH3 molecules by the enzyme nitrogenase – the source of ~50% of the N atoms in humans today; (ii) catalysis of H-atom transfer by enzymes of the vast radical SAM (S-adenosyl methionine) superfamily, comprising over 500,000 members, which initiate radical reactions by homolytic cleavage of SAM to form the highly reactive 5’-deoxyadenosyl radical (5’-dAdo•); (iii) Cu methane monooxygenase, which oxidizes methane to methanol and is central to mitigating emissions of methane, the potent greenhouse gas; (iv) in vivo speciation of Mn2+ as determined by EPR/ENDOR, for this cannot be achieved by cellular fractionation,  thereby identifying Mn2+ complexes with roles as primary defender against radiation, in controlling vertebrate fertilization, and as indicators of the likelihood of the persistence of viable lifeforms on Mars(!).

            Parallel studies of synthetic, biomimetic complexes provide constraints that help identify intermediates trapped during catalysis, and that are moreover of intrinsic importance as Jahn-Teller active systems that exhibit novel dynamic properties.

Selected recent publication illustrating these projects and exemplifying our approach can be found at the Northwestern Chemistry Department core-faculty website,



Preferred background: Magnetic Resonance (EPR/ENDOR), and/or Biochemistry, and/or Computational Chemistry.

Contacts welcomed ([email protected]) with Skype/Zoom conversations to follow

Open PhD positions in the Bordignon group – University of Geneve

We have two open PhD positions starting in spring 2022!

1. ABC Transporters
Are you interested in biophysics and membrane proteins? Are you ready to tackle a challenging project which combines quantum mechanics with novel in-cell experiments in a highly interdisciplinary environment? The task: Using EPR to study the effect of point mutations in a multidrug exporter in vitro and in cells.

Your profile: MSc in physics, physical chemistry or biophysics. A very good knowledge in quantum mechanics is mandatory, some experience in magnetic resonance methodology is desirable.

What we offer: Successful candidates will get the opportunity to participate in an interdisciplinary collaborative project between my group at the University of Geneva and the group of Prof. Seeger at the University of Zurich. They will be using state-of-the-art in-cell EPR methods and build up a strong and versatile scientific network. Our group strongly supports gender and diversity in science.

2. Liquid-Liquid Phase Separation
Are you interested in physical chemistry and liquid-liquid phase separation? Are you ready to tackle a challenging project which combines EPR, imaging, fluorescence, THz and Raman spectroscopy? The task: Using spectroscopy to understand how proteins’ dynamics and solvation change during the formation of liquid droplets.

Your profile: MSc in physics, physical chemistry or biophysics. A very good knowledge in thermodynamics is mandatory, some experience in magnetic resonance and optical spectroscopy is desirable.

What we offer: Successful candidates will get the opportunity to participate in an interdisciplinary project in my group at the University of Geneva. They will be using state-of-the-art EPR methods and build up a strong and versatile scientific network in the faculty of Science at UNIGE.

If you are interested, please send your CV, a motivation letter and reference letters directly to [email protected].

Postdoctoral position: Protein disorder in RNA-protein interactions: from dynamic structures to pathology

Postdoctoral position: Protein disorder in RNA-protein interactions: from dynamic structures to pathology
Jeschke group (EPR Spectroscopy). ETH Zurich, Zurich, Switzerland.
Project description:
In a Sinergia project funded by Swiss National Science Foundation, we address structure and functional relevance of intrinsically disordered protein domains (IDDs) of RNA-binding proteins. This includes liquid-liquid phase separation phenomena, which underlie formation of transient membraneless organelles, such as stress granules. We collaborate with the groups of Ben Schuler (University of Zurich, single-molecule FRET), Frédéric Allain (ETH Zurich, NMR), and Magdalini Polymenidou (University of Zurich, cell and tissue biology, superresolution microscopy).
Our part of the project uses continuous-wave EPR, Overhauser DNP measurements of water accessibility, and distance distribution measurements by double electron electron resonance (DEER) for obtaining information on structure and dynamics of (IDDs) in the dispersed and condensed state at ambient temperature and after fast freezing. We generate ensemble models by integrating information from EPR, NMR, small-angle scattering techniques and, potentially, FRET.
The successful candidate will design and develop spectroscopically orthogonal spin labelling methodology, use DEER and NMR paramagnetic relaxation enhancement (PRE) measurements to gather restraints for integrative structure modelling, and will be involved in further development of our modelling approach.
The candidate is either an NMR spectroscopist with experience in biochemistry and biophysics, who is interested in EPR spectroscopy or an EPR spectroscopist with interest in biological applications and in NMR. Candidates should have a PhD in chemistry, biochemistry, or biophysics.
Interested candidates should send a C.V., motivation letter and the names of two referees to [email protected]. Deadline 15th May 2022.
Facilities and Competence: We are situated at the Hönggerberg campus of ETH Zurich, in easy commuting distance to the city campus of ETH and to the Irchel campus of University of Zurich. For this project, we have a share in wet-lab facilities and NMR spectrometers of the Allain group in the Department of Biology of ETH.
Our group operates fully equipped commercial pulsed EPR spectrometers at X-, Q-, and W-band frequency and home-built spectrometers at S-, X-, and Q-band frequencies, among them two unique ultra-wideband home-built spectrometers at X- and Q-band frequencies. We develop the protein ensemble modelling package MMMx (https://mmmx.info) that uses distance distribution information for specifying ensemble width.
Jeschke group:
Relevant publications of the group
G. Jeschke, L. Esteban-Hofer, Methods in Enzymology, in press, doi: 10.1016/bs.mie.2022.02.010 (2022) Integrative ensemble modeling of proteins and their complexes with distance distribution restraints
I. Ritsch, L. Esteban-Hofer, E. Lehmann, L. Emmanouilidis, M. Yulikov, F. H.-T. Allain, G. Jeschke, Frontiers in Molecular Biosciences 8, 636599. doi: 10.3389/fmolb.2021.636599 (2021) Characterization of Weak Protein Domain Structure by Spin-Label Distance Distributions.
L. Emmanouilidis, L. Esteban-Hofer, F. F. Damberger, T. deVries, C. K. X. Nguyen, L. Fabregas Ibanez, S. Mergenthal, E. Klotzsch, M. Yulikov, F. H.-T. Allain, Nature Chemical Biology 17, 608-614 doi: 10.1038/s41589-021-00752-3 (2021) NMR and EPR reveal a compaction of the RNA-binding protein FUS upon droplet formation
G. Jeschke, Protein. Sci. 30, 125-135 doi: 10.1002/pro.3965 (2021) MMM: Integrative ensemble modeling and ensemble analysis
G. Masliah, C. Maris, S. L. Konig, M. Yulikov, F. Aeschimann, A. L. Malinowska, J. Mabille, J. Weiler, A. Holla, J. Hunziker, N. Meisner-Kober, B. Schuler, G. Jeschke, F. H. Allain, EMBO J. 37, UNSP e97089 (2018), Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains
G. Jeschke, Emerging Topics in Life Science, 2, 9-18, doi: 10.1042/ETLS20170143 (2018) The contribution of modern EPR to structural biology
C. Gmeiner, G. Dorn, F. H. T. Allain, G. Jeschke, M. Yulikov, Phys. Chem. Chem. Phys. 19, 28360-28380 (2017) Spin labelling for integrative structure modelling: a case study of the polypyrimidine-tract binding protein 1 domains in complexes with short RNAs
G. Jeschke, Proteins 84, 544-560 (2016), Ensemble models of proteins and protein domains based on distance distribution restraints
O. Duss, M. Yulikov, F. H.-T. Allain, G. Jeschke, Methods in Enzymology, 558, 279-331 (2015) Combining NMR and EPR to Determine Structures of Large RNAs and Protein–RNA Complexes in Solution
O. Duss, E. Michel, M. Yulikov, M. Schubert, G. Jeschke, F. H.-T. Allain Nature, 509, 588-592. (2014) Structural basis of the non-coding RNA RsmZ acting as protein sponge

Research Fellow in Electron Paramagnetic Resonance (EPR) Spectroscopy

We have a 3 year postdoctoral research fellow position in EPR spectroscopy, available in the Pliotas Lab (pliotasgroup.org) in the Astbury Centre (astbury.leeds.ac.uk), at University of Leeds. The BBSRC-funded project involves the application of PELDOR/DEER distance measurements (Qband) on spin labelled protein complexes to elucidate their mechanism and dynamics. The application deadline is on the 7th of January 2022.

The project will involve regular trips to the national EPR facilities in Manchester consisting of Bruker cwEPR (L-, S-, X-, K- and Q-bands), pulse-EPR (X-band, 2K base temperature; Q/Sband, 2K; X-band 7K, with AWG technology) to set up and perform PELDOR/DEER experiments. The postholder will also perform PELDOR/DEER distance restrained Molecular Dynamics, using the Arc3&4 supercomputers in Leeds, complemented by CryoEM and HDX-MS measurements.

For more details on this post and how to apply please check the following link: https://jobs.leeds.ac.uk/vacancy.aspx?ref=FBSBM1160

Interested applicants should contact directly Dr Christos Pliotas ([email protected]) for informal inquiries.

PhD opportunity: Next generation electrochemical EPR techniques to study redox flow reactions

Supervisors: Maxie M Roessler (Imperial College London), John JL Morton (University College London), Anthony R Kucernak (Imperial College London)

Unpaired electrons have an impact on our society on many levels, e.g. in IT/communication (the modern computer) and in fundamentally understanding enzymes underpinning disease or bioinspired technology. We will take advances in the field of quantum technologies and electrochemistry and apply them to electron paramagnetic resonance (EPR) to enable novel applications.

Electrochemical EPR is currently limited by the desire to use highly ionically-conductive solutions for electrochemical purposes with a preference for low relative permittivity materials for EPR, leading to a conflict in requirements. We recently demonstrated the first direct potential control of redox centres in molecules of any size through film-electrochemical EPR (FE-EPR). In this project we will use microresonators to generate spins at the point of maximum sensitivity, simultaneously acting as EPR resonator and working electrode (WE), enabling optimal conditions for both electrochemistry and EPR for the first time. Eliminating the ‘conductivity compromise’ and diffusion of the redox-active species to the WE through surface confinement should enable microresonator FE-EPR to investigate the formation, evolution and nature of very low-concentration radicals during (electro)catalysis and charge storage and hence have a far-reaching impact across many disciplines.

We propose to: (1) Demonstrate proof-of-concept of microresonator FE-EPR (using Au-coated micro-resonators, providing a versatile surface for functionalization); (2) Show its first application to charge generation and storage in battery-relevant non-aqueous and aqueous redox centres such as non-aqueous organic redox species for flow batteries; (3) Apply the technique to biomaterials, to understand how the bacterial protection system MsrP/Q, found in major human pathogens, functions.


Candidates must apply to the Centre for Doctoral Training in the Advanced Characterisation of Materials in London (ACM CDT) in the first instance (deadline 14th of December, interviews in January): https://www.jobs.ac.uk/job/CKW470/epsrc-and-sfi-centre-for-doctoral-training-in-the-advanced-characterisation-of-materials-cdt-acm-industrial-phd-studentships

Informal enquiries welcome ([email protected])

Post-doctoral position for the implementation of EPR spectroscopy in the UNC Chapel Hill Department of Chemistry’s NMR Core Laboratory 

The EPR Post-Doctoral Scholar in the NMR Core plays a key role in implementing and expanding the use of EPR spectroscopy in the Core while also supporting NMR spectroscopy consistent with their expertise.  This individual will collaborate with faculty, post-docs and students in magnetic resonance as well as train users and assist with the maintenance of instrumentation.  The position is designed to enhance and develop managerial skills while expanding technical expertise in magnetic resonance.


The research role (50%) includes a heavy emphasis on developing standard and advanced operating procedures in EPR spectroscopy and sharing capabilities with students and researchers.  Training, seminars and advanced training workshops are expected along with simulations and direct consultation and collaboration with research groups.  EPR applications include low temperature, time resolved experiments and the monitoring of light induced chemistry.


The laboratory management role (50%) involves working with the laboratory team to maintain a readily accessible and reliable collection of instrumentation for the acquisition of EPR and NMR data.  This includes coordinating with core staff to support high throughput runs using the sample changers on NMR spectrometers, general maintenance of EPR and NMR spectrometers and associated magnets, diagnosing instrument issues and assisting and training users in both EPR and NMR spectroscopy.  Additional experience in managing a major magnetic resonance laboratory is possible, consistent with abilities.


Contact: Marc ter Horst, PhD.   NMR Core Laboratory Director

[email protected], 919-843-5802

f-Element Molecular Magnetism / EPR Postdoctoral Opportunity @ NHMFL

The position is funded by the US Department of Energy program “Materials and Chemical Sciences Research for Quantum Information Science”. The project, titled “Molecular f-Element Qubits with Controllable Quantum Coherence and Entanglement”, is led by Stefan Minasian at Lawrence Berkeley National Laboratory (LBNL), with collaborators at UC Berkeley and the MagLab. Work at the MagLab involves application of advanced high-field/frequency pulsed EPR methods to the study of molecular lanthanide and actinide complexes with a view to their potential use in quantum information science applications. The successful applicant would have access to world-class facilities and an outstanding network of collaborators.


Expectations include a willingness to learn new techniques and concepts, and an ability to contribute intellectually to the Department of Energy Project that will fund the position. Primary duties include: (i) operating advanced instrumentation at the MagLab and collecting EPR data on samples provided by collaborators, primarily molecular magnetic lanthanide and actinide complexes; (ii) spearheading efforts aimed at analyzing and interpreting the results of these experiments; and (iii) developing drafts of manuscripts describing this work, with a view to publication in leading journals. Funds are available within the project (and from other sources) that will allow travel to present research outcomes at regional, national and international conferences. The successful candidate is expect to be able to work independently, whilst also recognizing that they will be part of a larger collaborative team involving immediate group members, MagLab scientists and external collaborators.



Stephen Hill

[email protected]

Postdoctoral research positions at Argonne

The Solar Energy Conversion Group at Argonne National Laboratory is looking for two postdoctoral appointees to study quantum spin phenomena following light-induced charge transfer in photosynthetic proteins using advanced EPR spectroscopy – see link below for a detailed description. The positions are open until candidates are chosen.

Please, forward this message to qualified candidates which may be interested in this position.


Postdoctoral research position: Quantum circuits for ultra-low volume EPR spectroscopy

The post-doctoral project will center on developing and building an Electron Spin Resonance (EPR) spectroscopy tool based on quantum circuits technology. The aim of the project is to demonstrate the ability to detect and characterize samples with ultra-small volumes. The gain in absolute and concentration sensitivity will be based on earlier developments [1-2] based on quantum circuits techniques, in particular high quality factor small mode volumes superconducting resonators and quantum-limited amplifiers. The candidate will namely work on building fast tunable matching circuits and integrated broadband quantum-limited detection circuits to extend these early experiments to short-lived species. A successful implementation of these circuits will enable the applicant to measure target species encompassing typical EPR characterization species, nitroxide labels and other markers, and protein crystals. The post-doc will take place in the Quantum circuits group at ENS de Lyon, which is an expert in quantum circuit technologies for quantum sensing and quantum information processing.

An ideal candidate will thus have background in pulsed EPR (or NMR), and/or experimental superconducting circuits and/or quantum systems in condensed matter. Experience in the following will be appreciated: pulsed EPR schemes, nanofabrication, low-temperature measurements, and/or microwave instrumentation and design.

If you like experimental physics, want to enjoy living in one of the world food capitals and its nearby outdoors attractions, don’t hesitate to reach out! Informal enquiries should be sent to Dr Audrey Bienfait ([email protected]). Further details on the position and application process can be found on the application website. We are looking to fill this position as soon as possible, preferably in the Fall 2020. The position is for one year, with possible extension.

[1] A. Bienfait et al., Nature Nanotechnology, 11, 253–257 (2016)
[2] V. Ranjan et al., Applied Physics Letters 116 (18), 184002 (2020)

PhD and Postdocs to combine new methods at the interface between EPR and NMR spectroscopy

The Max Planck Institute for Biophysical Chemistry is one of the largest institutes of the Max Planck Society for the Advancement of Science and conducts basic research to advance knowledge and benefit society. Innovative projects and interdisciplinary cooperation characterize research within the Max Planck Society. The research group of Electron Paramagnetic Resonance (EPR) spectroscopy (Prof. Dr. Marina Bennati) invites applications for positions as

PhD and Postdocs(f/m/d)

The positions are funded by the ERC advanced grant Bio-enMR, which aims at establishing spectroscopic methods at the interface between EPR and NMR spectroscopy. Specifically, we develop electron nuclear double resonance and liquid-state dynamic nuclear polarization for the investigation of bio-macromolecules, for instance the interaction of enzymes with drugs. Work will include collaborative research at the national and international level.

Your Profile:

Master/PhD or equivalentacademic degree in Physics or Chemistry
background in magnetic resonance spectroscopy
experience in the field of either EPR or NMR (for a Postdoc position)

Additional Information: PhD students will have the opportunity to participate in one of several available PhD programs of the Göttingen graduate schools with four years funding. Postdoc positions are limited to two years with possibility of extensions. The positions are available from October 2021 but the starting date is flexible.

Payment and benefits are based on the TVöD guidelines.The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals.The Max Planck Society strives for gender and diversity equality. We welcome applications from all backgrounds.

Please submit your application including a short letter of motivation, CV, a list of publications, and email addresses of two referees preferably via e-mail as a single PDF file to

[email protected]
Max Planck Institute for Biophysical Chemistry
Electron Paramagnetic Resonance Spectroscopy
Prof. Dr. Marina Bennati
Am Fassberg 11
37077 Göttingen

Information pursuant to Article 13 DS-GVO on the collection and processing of personal data during the application process can be found on our website below the respective job advertisement.

Post Doc @ Goldfarb Lab

Post-doctoral positions in the Goldfarb group at the Weizmann Institute of Science.
I have a couple of post-doc positions in my lab on the development and applications of pulse EPR distance measurements on proteins inside cells. The aim is to probe structure of proteins in their native environment, to explore conformational changes due to interaction with other proteins and ligands in the cell, and detect response to cellular processes that may lead to conformational changes. This is based mainly on the use of Gd3+ spin labeling schemes, but not only, that are compatible with the reductive environment of the cell. This includes the development of new in-situ labeling schemes, expanding the measurements to include ENDOR (electron-nuclear double resonance) techniques. In terms of specific biological systems we are interested in the focus is the Hsp90 chaperon and its interaction with drugs.
Background required: Molecular Biology/Biochemistry and/or Magnetic Resonance (NMR or EPR).
Information about the Weizmann Institute and its post-doctoral program can be found at http://www.weizmann.ac.il/ and https://www.weizmann.ac.il/feinberg/admissions/about-program, respectively.
For those who are interested, or have any questions please contact :
Professor Daniella Goldfarb
Department of Chemical and Biological Physics
Weizmann Institute of Science
Rehovot, 76100 Israel
E. Mail : [email protected]

Professor on THz spectroscopy

A new open position for an associate or full professor on THz spectroscopy in high magnetic fields. at Radboud University Nijmegen, Netherlands.


PhD position in transient pulse EPR and optical spectroscopy

Applications are invited for a doctoral position to work in the group of Dr. S. Richert within the Institute of Physical Chemistry at the University of Freiburg, Germany.

The project aims at investigating the factors influencing spin-information transfer in organic multi-spin systems by combining modern optical spectroscopy and pulse EPR. Through the work on the project, the successful candidate will be made familiar with (i) state-of-the-art pulse EPR methods and (ii) modern optical spectroscopic techniques from the femtosecond to the microsecond time scale and learn about their applicability to current research challenges in the field of molecular spintronics.
Depending on the strengths and interests of the successful applicant, the focus of the individually designed subproject may either lie on the theoretical (programming, data analysis and simulations, method development) or practical (spectroscopic measurements, synthesis) aspects of the project. For further details please see: https://www.richert.uni-freiburg.de

Highly motivated candidates with a master’s degree (obtained no longer than three years ago) in either chemistry or physics are strongly encouraged to apply. Successful applicants should have a solid background in physical chemistry (spectroscopy), good presentation and writing skills in English and/or German, and must be able to work independently as part of a team in an interdisciplinary environment. Previous experience with programming (MATLAB, Python), advanced optical spectroscopy, or magnetic resonance spectroscopy, is advantageous, but not required.

For details regarding the application process and possible starting dates please contact Dr. S. Richert.

  [email protected]
Postdoctoral Fellow in Biochemistry and Molecular Biology (2020-00410)

Postdoctoral fellowship in biophysics and structural biology of signaling kinases and membrane transporters

We are looking for highly motivated applicants for a postdoctoral fellow in the Edward A. Doisy Department of Biochemistry and Molecular Biology at Saint Louis University, beginning in the spring of 2020. Successful candidates are expected to have a doctoral degree in chemistry, biochemistry, or biophysics, with research experience in structural biology/spectroscopy (EPR spectroscopy, Electron Cryomicroscopy, or X-ray crystallography). The lab focuses on the molecular understanding of the cellular release mechanism of the brain-type creatine kinase and sphingosine kinase isoforms 1 and 2 as key therapeutic targets in a wide variety of neoplastic, cardiovascular, and neurodegenerative diseases. In addition, the lab investigates the structural dynamics of membrane transporters associated with the survival of metastatic cells. Projects will combine EPR restraint-assisted modeling with other structural studies. Applicants should be able to think critically and demonstrate productivity throughout previous research experiences. Compensation will be competitive based on experience.

The Doisy Research Center EPR facility is equipped with an EMX X-band continuous-wave (CW) EPR spectrometer, and a Bruker ELEXSYS E580 pulse EPR spectrometer capable of pulse and CW EPR spectroscopy at both X and Q-bands, as well as a variety of ELDOR and ENDOR spectroscopies. The candidate will have access to a Phoenix robotic instrumentation from Art Robbins Instruments for the preparation, screening, and imaging of crystals and two Rigaku X-ray generators for the collection of high-resolution data on macromolecular samples (https://biochem.slu.edu/facilities-resources/). Cryo-EM images will be collected on a state-of-the-art Titan Krios G3 300kV Cryo-TEM available at our affiliated WUCCI center (https://wucci.wustl.edu/facilities/cryo-em/).

Online Application Form:

PhD position: DNP/MAS NMR using photo-excited triplet states

The research group of Dr. Guinevere Mathies in the Department of Chemistry at the University of Konstanz is looking for an enthusiastic PhD student to join our international team. He or she will investigate if and how the high polarization generated in the photo-excited triplet states of organic molecules can be used for Dynamic Nuclear Polarization (DNP). This project is part of a larger effort in our group to develop new forms of DNP to enhance the sensitivity of high-resolution magic-angle spinning (MAS) NMR.

The candidate we look for has a MSc degree in Physics, Chemistry or a related field and research experience in EPR spectroscopy is very welcome. He or she is highly motivated, driven by curiosity, and can work independently as well as in a team.

The PhD position is planned for 3 years with the possibility of extension and a salary according to the German TVL E13 67% scale. It is available immediately and applications will be considered until the position is filled. To apply, send a cover letter and a CV to Dr. Guinevere Mathies at [email protected].

For more information, visit our website: https://www.chemie.uni-konstanz.de/mathies

Postdoctoral Scientist Position (Biochemistry & ESR Spectroscopy)

The Macromolecular Electron Spin Resonance (ESR) Spectroscopy group located in the Institute of Biophysics at Goethe University Frankfurt invites application to fill a Postdoctoral Scientist position as soon as possible. Our group investigates the functional mechanism of membrane-embedded heterooligomeric macromolecular machines using ESR spectroscopy as the primary research tool complemented with further structural and biophysical techniques. The Postdoctoral Scientist will work on elucidating the molecular mechanism of the lipopolysaccharide transport (Lpt) system. Please visit our homepage for further details of the project (www.in-situ-esr.de). The Institute has a diverse research program including IR spectroscopy, theoretical biophysics, and cryo-electron microscopy. Thus many opportunities exist for collaborative research in these directions.

The ideal candidate has a PhD in Biophysics, Biochemistry, or Chemistry. Experience in molecular biology techniques and membrane protein expression/purification is desired. Knowledge in ESR spectroscopy or another structural biology tool will be considered as a bonus. Scientific curiosity, good communication skills, and ability to work in an international environment are essential. The position is embedded within the framework of the Center for Biomolecular Magnetic Resonance (BMRZ), which hosts state-of-the-art EPR and NMR spectrometers. We offer a position for three years (further extension is possible) with salary and benefits according to the German collective labor agreement for public service (TV-G-U). Our Institute is located close to Frankfurt, which is a cosmopolitan and culturally diverse city. The University advocates gender equality and therefore strongly encourages women to apply. People with disabilities are given preference if equally qualified.

Interested candidates may send the application (including motivation letter, CV, names of referees, and copies certificates in one PDF file) to Benesh Joseph (email: [email protected]). Find more about us at www.in-situ-esr.de.

Postdoctoral research position in ESR quantum information processing

An open postdoctoral position at the Institute for Quantum Computing (IQC), University of Waterloo, focuses on the application of coherent control techniques in ESR to address challenges in the field of quantum information processing. Recent research in our group has spanned topics including algorithmic cooling, randomized benchmarking of quantum gate fidelities, and closed-loop (feedback) methods for quantum control. A successful candidate will have obtained a PhD in Physics, Chemistry or related fields with an emphasis in ESR spectroscopy. Experience with pulsed methods such as ESEEM and pulsed ENDOR is strongly preferred.

IQC is a world-leading institute for research and education in Quantum Information. Its 30 faculty members lead thriving research programs spanning the areas of Applied Mathematics, Chemistry, Combinatorics & Optimization, Computer Science, Electrical & Computer Engineering and Physics & Astronomy. IQC has significantly expanded its infrastructure to support experimental research, with a state-of-the-art nanofabrication and metrology centre. Our laboratory facilities include low-temperature pulsed ESR and ENDOR capabilities.

Interested applicants please contact Prof. Jonathan Baugh ([email protected]) or Prof. Raymond Laflamme ([email protected]) for more information on the position and how to apply. Applications will be accepted until the position is filled.

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