Post Doc @ Goldfarb Lab

Post-doctoral positions in the Goldfarb group at the Weizmann Institute of Science.
I have a couple of post-doc positions in my lab on the development and applications of pulse EPR distance measurements on proteins inside cells. The aim is to probe structure of proteins in their native environment, to explore conformational changes due to interaction with other proteins and ligands in the cell, and detect response to cellular processes that may lead to conformational changes. This is based mainly on the use of Gd3+ spin labeling schemes, but not only, that are compatible with the reductive environment of the cell. This includes the development of new in-situ labeling schemes, expanding the measurements to include ENDOR (electron-nuclear double resonance) techniques. In terms of specific biological systems we are interested in the focus is the Hsp90 chaperon and its interaction with drugs.
Background required: Molecular Biology/Biochemistry and/or Magnetic Resonance (NMR or EPR).
Information about the Weizmann Institute and its post-doctoral program can be found at http://www.weizmann.ac.il/ and https://www.weizmann.ac.il/feinberg/admissions/about-program, respectively.
For those who are interested, or have any questions please contact :
Professor Daniella Goldfarb
Department of Chemical and Biological Physics
Weizmann Institute of Science
Rehovot, 76100 Israel
http://www.weizmann.ac.il/chemphys/EPR_group/
E. Mail : daniella.goldfarb@weizmann.ac.il